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Anxiety and Depression link to Gut Inflammation

By Sue Kira naturopath/nutritionist

Many people suffer from the debilitating effects of anxiety and depression and studies have shown a link between these symptoms and inflammation in the gut and leaky gut.

Interestingly, the incidence of anxiety and depression is increasing, while the incidence of poor gut health also increases. A coincidence?

After consulting with more than 15,000 clients, I estimate that at least 85% of them (and that’s being conservative) had gut issues that adversely affected their health.

Why is poor gut health on the increase? Reasons include poor diet, denatured food, less time spent in the kitchen, fast food, the overuse of antibiotics…and more.

Other key factors are stress and elevated cortisol, low cortisol or cortisol resistance. Cortisol resistance is where the body doesn’t recognise or is resistant to the message from cortisol that there is a stress response in the body. Kind of like ‘the boy who cried wolf’ syndrome.

Cortisol is our body’s way to deal with stress and inflammation but if either are prolonged then we can create ‘resistance’ and therefore the cortisol no longer reduces inflammation even if cortisol levels are high. The result of this is a prolonged inflammatory state.

Inflammation signals the release of white blood cells called Monocytes into the blood, which turn on proinflammatory genes that lead to the release of inflammatory cytokines.

Once triggered, the inflammatory cytokines talk to the central nervous system, via the Vagus nerve, which connects the gut and the brain, activating microglia in the brain, releasing an enzyme called IDO (indoleamine 2, 3-dioxygenase) which stimulates production of biomolecules that can result in symptoms of anxiety, restlessness, agitation or even panic attacks.

We often relate the cause of anxiety and depression to a brain biochemistry fault, when the cause could indeed be coming from the gut being inflamed, leaky or dysbiotic (wrong balance of bacteria).

Consider this: if medication for anxiety or depression is working, then the cause may well be a brain biochemistry imbalance; but if medication is not working effectively, the cause could be related to gut issues. It’s worth checking.

There are many ways to check if you have gut inflammation. In clinic, I use Live Blood screening to view the red and white blood cells. I also use external tests, particularly the gut microbiome testing that looks at things like leaky gut, digestion markers, bacteria levels (good and bad), viruses, parasites and fungi like Candida species.

The right tests provide valuable information which may uncover underlying causes of anxiety, depression, restlessness and generally feeling out of sorts.

If you would like to book an in-clinic, skype or phone consultation which may help to unravel the root causes, please find the booking link on the Home Page or under the Clinic tab.

I look forward to meeting you to help you reclaim your vitality.
With love, Sue Kira N.D

Understanding Methylation

Introduction to understanding methylation

The process of methylation if working properly is what keeps us healthy. Without methylation we cannot survive and methylation defects are biochemically what contribute greatly to who we are, what we look like, how we act but is also central to our physical, mental and emotional wellbeing.

Methylation regulates the switching on and off of our genes and silences viruses. When functioning optimally, methylation keep the less desirable genes switched off, such as those that cause birth defects, cancers and auto-immune disease for example, whilst allowing the switching on of genes that help our body systems run effectively. We call this gene expression.

We may go about our day to day lives never being aware of these processes and meanwhile this process is making, maintaining and repairing our DNA, which is our genetic coding. We can get an ‘epigenetic’ effect whereby how we chose to live our lives can have an effect on our gene expression and it is these events, stressors and loving care that help either support or hinder the natural process of building and repairing our body.

In this article I will be covering the following topics:

  • Introduction to methylation
  • What is methylation
  • Testing for methylation
  • Biochemistry of UNDERMETHYLATION
  • Biochemistry of OVERMETHYLATION
  • Things that can affect methylation
  • Methylation impairments
  • What is homocysteine?
  • Causes of Elevated Homocysteine
  • Risks Associated With Elevated Homocysteine Levels
  • What is the hereditary predisposition MTHFR?
  • Symptoms of MTHFR gene copying errors
  • Anemia, DNA, and Folate
  • Methylmalonic Acid (MMA)
  • Folates, folic acid and unmethylated folic acid (UMFA)
  • Dangers of UMFA
  • Supplementation to support under or overmethylation

What is methylation

Methylation begins with a what is termed a ‘methyl group’ which is basically a carbon and three hydrogen atoms joined together and this group is then transformed to another compound. So if we use a situation to compare it to it would be like at a work place where one person passes an envelope containing a group of objects to another person at work who then has the job of making those bits into another component that is then passed onto someone else to finish the job to have a completed job order.

There are certain points within the methylation cycle where each have a certain job to do for beginning, carrying out and finishing the job. In other words each part has its role and ‘job description’ to do to get the job done.

Our nerve functions is highly dependent on proper methylation as each nerve requires the proper nerve insulation just like the wires in our house or car otherwise it will be like exposed wires and this can lead to symptoms of physical, emotional or behavioural changes. Methylation switching on and off of genes also control the production and breakdown of neurotransmitters which are our chemical messengers in the brain and nervous system as well as in the gut and many other places of importance.

The nervous system communicates with immune cells, so a faulty methylation process can lead to immune imbalances, which can turn a simple cold or flu into pneumonia or and auto-immune disease. An efficient methylation system will create an efficient communication system to sound the alarm bells of immune invaders. Methylation also immobilise fats and cholesterol so they can be removed by the body without clogging up arteries and organs, so improving methylation cycles can help the body to naturally clear cholesterol and fats that would otherwise lead to heart attacks, high blood pressure, diabetes and fatty liver disease.

There are so many other things that methylation supports such as hormones, regulating oestrogen and testosterone as examples, but also thyroid hormones, adrenal hormones and the list goes on.

Methylation regulates histamine levels which is why someone who gets allergies we call an under-methylator, because the body is unable to break down the histamine. Histamine is hormone that is often over expressed in cases of allergies, eczema, asthma and even anaphylactic reactions.

To summarise, methylation is involved in many of our most vital bodily functions, by offering support and/or managing, such processes as:
1) Detoxification
2) Controlling inflammation
3) Maintaining DNA
4) Immune function
5) Energy production
6) Mood balancing

Some of the conditions linked to poor methylation include but not limited to; cardiovascular disease, cancer, diabetes, neurological conditions, autistic spectrum disorders, chronic fatigue syndrome, Alzheimer’s disease, miscarriages, fertility, and problems in pregnancy, allergies, immune system, digestive problems, mood and psychiatric disorders as well as the aging process.

Tests for methylation (under and over)

Whole blood histamine (an important protein involved in many allergic reactions), Basophil count (a type of white blood cell), zinc and copper levels, homocysteine, and heavy metal and mineral balances.

The common biochemistry of UNDERMETHYLATION is:
1. High blood histamine
2. High basophil count
3. Low plasma zinc
4. Elevated serum copper
5. Low homocysteine
6. High heavy metals
7. Low levels of the neurotransmitters serotonin, dopamine and norrpinephrine.

As proper methylation is a major factor in the production of serotonin, dopamine, and norepinephrine in the body, undermethylation can lead to a depletion of these three essential neurotransmitters and can also result in some of the following characteristics – phobias, delusional behaviour, obsessive compulsive disorder (OCD), frequent headaches, denial of illness and non compliance, difficultly with transitions, seasonal allergies, high achiever, a strong will, highly motivated, addictive behaviour, calm demeanour with high inner tension, social isolation and sparse hair growth.

The common biochemistry of an OVERMETHYLATION is:
1. Low blood histamine
2. Low basophil count
3. Low plasma zinc
4. Elevated copper
5. Elevated levels of the neurotransmitters serotonin, dopamine and norepinephrine.

Overmethylation can cause some of the following characteristics – high anxiety/panic, poor achiever and low motivation, artistic/musical ability, low libido and overweight, easily frustrated, sleep disorder and paranoia, depression and self isolation, self mutilation and nervousness, tinnitus (ringing in the ears), food/chemical sensitivities, high pain threshold, past history of ADHD, hyperactive psychosis, grandiosity, nil family history, hirsutism and eczema/dry skin.

Things that can affect methylation

Lack of the necessary precursors such as:

  • methionine
  • choline
  • betaine
  • homocysteine

Lack of co-factors:

  • B12
  • Folate
  • Zinc
  • B2, B3 and B6

Enzyme polymorphisms (genes)

  • MTHFR
  • COMPT

Methylation impairments

Impairment of methylation reactions could result in a condition of high levels of homocysteine known as hyperhomocysteinemia which can also be a marker of low levels of B12 and folate.

What is homocysteine?

Homocysteine is a chemical in the blood that is produced when an amino acid called methionine is broken down in the body. We all have some homocysteine in our blood, but high homocysteine levels, also called hyperhomocysteinemia, may cause irritation of the blood vessels which can increase the risk for hardening of the arteries which could eventually result in a heart attack and/or stroke, and blood clots in the veins, referred to as venous thrombosis.

Causes of Elevated Homocysteine

  • Deficiency of folate or B6 and B12
  • Kidney disease
  • Hypothyroidism
  • Medications such as methotrexate
  • Methylenetetrahydrofolate reductase (MTHFR) genetic fault
  • Psoriasis
  • Systemic lupus erythematosis

Risks Associated With Elevated Homocysteine Levels

  • Coronary artery disease
  • Heart attack
  • Stroke
  • Peripheral arterial disease
  • Venous thrombosis
  • Pulmonary embolism
  • Dementia
  • Neural tube defects in children

Let’s have a look at the main causes of elevated Homocysteine

If one of the causes of elevated homocysteine is MTHFR gene mutation, what does this mean?

What is the hereditary predisposition MTHFR?

Some people develop an elevated homocysteine level because of a genetic predisposition which then creates the methylation defect that affects the ability of the body to convert folate and thereby creating problems with regulating homocysteine levels in the body. We all have 2 MTHFR genes, one inherited from each parent for each of the two genes. Some people have a genetic mutation in one or both of their MTHFR genes. People with mutations in one MTHFR gene are called “heterozygous” for the MTHFR mutation, but if mutations are present in both genes, the person is said to be “homozygous” for the mutation.

The most common MTHFR mutation is called the MTHFR C677T mutation, or the “thermolabile” MTHFR mutation. Another common mutation is called MTHFR A1298C. To have any detrimental effect, mutations would usually be present in both copies of a person’s MTHFR genes. Even when 2 MTHFR mutations are present (eg, 2 C677T mutations, or one C677T mutation and one A1298C mutation), not all people will develop high homocysteine levels. Although these mutations do impair the regulation of homocysteine, adequate folate levels essentially “cancel out” this defect, especially if the folate is consumed from foods or the more active form of folate such as calcium folinate or better still is the 5MTHF.

Regardless of whether someone has an MTHFR mutation in both genes or not, the treatment for elevated homocysteine is the same—dietary intervention and supplementation with folic acid and vitamins B6 and B12. If supplementing, then the amount of each of these supplements should be adjusted on the basis of the degree of homocysteine elevation, not genetic status.

Symptoms of MTHFR gene copying errors

These can include fatigue, depression, cardiovascular disease, and other more vague complaints such as aches and pains and other symptoms.

A closer look into the world of B12 and folate:

There are two different co-enzyme forms of vitamin B12:

  1. Methylcobalamin
  • Used by the enzyme methionine synthase to turn homocysteine (HCY) into methionine (a methylation process).
  • Methionine is further converted to the important methyl donor, S-adenosylmethionine  also known as SAM or SAMe
  1. 5′-deoxyadenosylcobalamin
  • Used by the enzyme methylmalonyl-CoA mutase to convert methylmalonyl-CoA to succinyl-CoA.
  • Used by the enzyme leucine aminomutase to convert B-leucine into L-leucine and vice-versa.

Anemia and Folate

Traditionally, B12 deficiency, normally resulting from the poor ability to absorb B12, but also from poor methylation, was diagnosed by finding abnormally large red blood cells. This sort of anemia has two names:

  • Macrocytic anemia – when the average volume of the red blood cells, known as the Mean Corpuscular Volume (MCV), is larger than normal
  • Megaloblastic anemia – when abnormally large red blood cells are observed under a microscope

The vitamin folate (aka folic acid) affects the anemia symptoms of B12 deficiency. Folate is needed to turn uracil into thymidine, an essential building block of DNA. DNA is needed for new red blood cell production and division. B12 is involved in this process because in creating methylcobalamin (used in the HCY to methionine reaction), B12 produces a form of folate needed to make DNA. If there is no B12 available, this form of folate can become depleted. Lack of Anemia Does Not Mean B12 Status Is Healthy. Traditionally, the existence of macrocytic anemia was relied on to indicate a B12 deficiency. However, neurological disorders due to B12 deficiency commonly occur in the absence of a macrocytic anemia.

Methylmalonic Acid (MMA)

The second coenzyme form of B12, adenosylcobalamin, takes part in the conversion of methylmalonyl-CoA to succinyl-CoA. When B12 is not available, methylmalonyl-CoA levels increase. Methylmalonyl-CoA is then converted to methylmalonic acid (MMA) which then accumulates in the blood and urine. Since B12 is the only coenzyme required in this pathway, MMA levels are the best pathology test indicators of a B12 deficiency.

High MMA levels can also (but rarely) be caused by genetic defects, kidney failure, low blood volume, gut bacteria changes, pregnancy, and thyroid disease

Folic Acid

FOLATES, FOLIC ACID, AND UNMETHYLATED FOLIC ACID are the different forms of folate. Found in leafy green vegetables, natural folates are the group name for related members of this B-vitamin family. The synthetic form, folic acid (FA), is used in fortified foods and most dietary supplements.

  1. Folate. This form of the vitamin is found in our green vegetables. If you eat about 1.5 cups of cooked greens three or more times weekly you will obtain enough natural folate to overcome almost any genetic copying defect.  Folate is also found in meats, eggs and other foods, but not as much.  Some folate can also be made in the intestinal tract.
  1. Folic acid. This is a synthetic form of folic acid that is widely used in B vitamin supplements. This form is not converted as well to the active form of the vitamin in people with the copying weakness (MTHFR gene defects) and so creates point 5 below.

  This is a supplemental form of folate that is well utilised by most with the copying defect mentioned above.

  1. Folinic acid. This is a supplemental form of folate that is well utilised by most with the copying defect mentioned above.

  This is also a supplemental form of folate that is well-utilised by those with the copying defect.

  1. Methyl folate. This is also a supplemental form of folate that is well-utilised by those with the copying defect.
  1. Unmethylated or unmetaboilised folic acid (UMFA).

With increased consumption of folate fortified grains and the popularity of vitamin supplements, many people are getting too much synthetic folic acid. Unlike natural folate, synthetic folic acid is processed very slowly in the body even at the Australian Recommended Dietary Allowance (RDA) intake of 400 mcg per day (for adults), UMFA can be found in the blood stream for extended periods of time. UMFA should be monitored for anyone who takes vitamins and/or consumes products with fortified enriched grains and cereals. Monitoring is also strongly recommended for women who are pregnant or who are trying to become pregnant. It has been known to increase the feelings of ‘morning sickness’, so nutritional supplements with folic acid are not advisable with those who have the MTHFR gene defects and preferably should use the more active forms.

What is the danger of too much UMFA?

  • Depressed immune function
  • Enhanced development and progression of certain cancers
  • Anaemia, poor cognition, and impaired memory especially with low B12 status

When folate is properly processed it can support the body with:

  • Making red blood cells
  • Proper nerve function
  • Bone health
  • Healthy brain and memory
  • Proper immune system function
  • Cell production, especially in skin and the digestive tract
  • Prevention of neural-tube defects (cleft lip and palate, spina bifida) in a developing foetus
  • Preventing miscarriage

Supplementation to support under or over methylation

Undermethylation:

Those with undermethylation often respond well to methionine, SAMe, 5HTP, calcium, magnesium, omega-6 essential oils such as borage and evening primrose oil, B-6, inositol, and vitamins A, C, and E, plus zinc, TMG or DMG. They should avoid supplements containing folic acid, but can tolerate the more active forms where there is MTHFR defect, especially if Homozygous for the defect.

Overmethylation:

This condition is the biochemical opposite of undermethylation. Those with overmethylation usually respond well to folic acid, B-12 (active forms), niacinamide (B3), DMAE, choline, manganese, zinc, omega-3 essential oils (DHA and EPA) and vitamins C and E, but should avoid supplements of methionine, SAMe, inositol, TMG and DMG.

In conclusion we have seen how methylation supports the body to detoxify as well as adjusts and rebuilds components needed for all bodily processes so also helps to control inflammation, maintaining good DNA transcription, support our immune and cardiovascular systems and provide us with the energy needed for our daily tasks and importantly also gives us a healthy brain and mood.

Foods for pyrrole disorder

Best foods to eat or avoid with pyrrole disorder and foods rich in B6 and Zinc

I’m often asked, what are the best foods to eat if you have pyrrole disorder, what foods to avoid for supporting the body, and what foods are rich in b6 and zinc to help balance pyrrole naturally. Whilst for many the best way to treat pyrrole disorder is with the use of supplementation, there are many that find that they are just too reactive to these supplements, can’t find the right dose, or simply just can’t afford treatment on-going.

Please note that the following cannot replace a treatment program that needs high doses, but it can help those that have only low levels of pyrrole, or are managing their stress well and have addressed other health imbalances such as gut issues e.g. leaky gut. These suggestions are also good for little ones whose parents find it difficult to supplement in the usual way, but most importantly the following can be good adjunctive therapy for all with pyrrole disorder, hormonal imbalances, digestion problems, neurotransmitter imbalances e.g. mental health problems and general good health.

Foods and drinks to avoid:

Pyrrole disorder is a condition associated with the liver (see pyrrole disorder article) so therefore anything that can affect the liver has a potential to undermine the good efforts done elsewhere to support the liver and pyrrole disorder. More often than not people with pyrrole disorder find that they are having increasing sensitivity to these substances anyway so it makes good sense to avoid them wherever possible.

These are alcohol, caffeine in coffee, black tea, caffeinated drinks, colas, sports drinks, energy drinks, and caffeinated pre gym workout mixes. Any drug, medication or pain killer can put extra stress and workload on the liver, but having said that, if you are on prescription medication you can’t just stop these without the recommendation from your health care practitioner.

Some are worse than others, for example, codeine and paracetamol strongly affect the liver and can also rob the liver of glutathione, a powerful antioxidant amino acid that the liver uses to detoxify. So other options for pain relief can be the ibuprofen class of drugs or anti-inflammatory herbs, spices and oils (as prescribed by your health care provider).  Some of these will still affect the liver but not rob the body of as much glutathione.

The foods that seem to affect those with pyrrole are those that are more difficult to digest, or foods that you are intolerant or allergic to. Most common foods and food substances that are best avoided include foods containing gluten or dairy, foods that are heavily processed, or have artificial ingredients, food coloring and preservatives, nitrates from hams, bacons, smoked foods and small goods. The more natural and unprocessed a food is the better for the liver, pyrrole disorder and good health in general.

Then we can look at what foods are rich in the vital nutrients needed for pyrrole disorder. These being B6 and Zinc. Of course there are also other important nutrients such as magnesium, Vit e, selenium, boron etc, but we will focus on the main ones here today.

Foods rich in B6 and Zinc

B6 rich foods: (20mg per day is a good minimum)

Rice Bran – Rice bran contains the most vitamin B6 with 4.07mg per 100g serving and can make a nice breakfast cereal topped with one of the new blended coconut rice milks or almonds milks if no nut allergies.

Dried Herbs and Spices – Although dried herbs and spices are rarely used in large portions, adding in a few extra pinches to all your sauces, soups, and stews is a great way to get more vitamin B6 into your diet. Chilli powder contains the most vitamin B6 with 3.67mg of vitamin B6 per 100g. Paprika has 0.28mg per tablespoon, garlic powder 0.22 per tablespoon, dried tarragon, ground sage, dried spearmint, basil, chives, turmeric, bay leaves, rosemary, dill, onion powder, oregano, and marjoram (all around 0.1-0.2mg per tablespoon).

Pistachios – are a delicious snack and a great addition to salads. 100 grams of raw pistachios will provide 1.7mg of vitamin B6. Roasted pistachios will provide 1.27mg per 100 gram

Garlic provides a host of health benefits and is also a great source of vitamin B6. Raw garlic is a great base to salad dressings, and also makes a good condiment. 100 grams of raw garlic provides 1.235mg of vitamin B6, 0.04mg per clove or teaspoon.

Liver– is a vitamin rich food that is most commonly found in the form of pâtés and sausages. Most any kind of liver provides a lot of vitamin B6, but turkey liver provides the most with 1.04mg in a 100 gram serving, or 0.86mg in an average turkey liver. Beef liver provides 1.03mg of vitamin B6 per 100 gram serving. All organ meats are rich in B6.

Fish (Tuna, Salmon, and Cod) Fish is a heart healthy food and a good source of protein. Yellow-fin Tuna provides the most vitamin B6 with 1.04mg per 100g serving. Atlantic salmon provides 0.94mg per 100 gram serving, 1.45mg in half a fillet.

Sunflower and Sesame Seeds (e.g. as Tahini) Sunflower and Sesame seeds are great as an addition to salads, as well as a snack on their own. Sunflower seeds provide 0.81mg of vitamin B6 per 100 gram serving, or 1.1mg per cup. Whole roasted sesame seeds provide 0.8mg per 100 gram serving, 1.1mg per cup. Sesame butter, or tahini, will provide 0.15mg of vitamin B6 per 100 gram serving, 0.04mg.

Pork Tenderloin (Lean) Lean Pork Tenderloin, also a zinc rich food, provides the most vitamin B6 when cooked roasted. Pork tenderloin contains 0.74mg of vitamin B6 per 100 gram serving. Other grass fed meat is also rich in B6

Hazelnuts – Dry roasted hazelnuts provide 0.62mg of vitamin B6 per 100 gram serving.

Egg yolk – especially raw is a good source of B6 providing 0.05mg per egg

Zinc rich foods (15mg per day is a good minimum)

Seafood Zinc in 6 cooked Oysters 76.4mg Other Seafood High in Zinc – Crab and Lobster 2.5mg per 100g.

Beef and Lamb Zinc in 100g meat 5mg

Spinach – 0.8mg Zinc in 100g Cooked or Raw

Other Green Leafy Vegetables High in Zinc – Amaranth Leaves, Endive, Radiccio, Rocket 0.2per 100g

Pumpkin and Squash Seeds Zinc in 100g -10.3mg Other Seeds High in Zinc – Sunflower, Chia and Flaxseeds. Sesame seeds or tahini 7mg per 100g

Nuts – Cashews Zinc in 100g – 5g Other Nuts High in Zinc – Pine nuts , Pecans, Almonds, Walnut, Peanuts, and Hazelnuts av 1gm per 100g .

Pork & Chicken Zinc in 100g pork Steak 1.5mg. Chicken is also High in zincT 2mg per 100g

Beans – Mung Beans, Baked Beans, Adzuki, Chickpeas, and Kidney Beans. 0.5mg Zinc in 100g

Mushrooms Zinc Per 14g Mushroom 1mg

 

 

Common adjunctive testing to pyrrole

Common adjunctive testing done alongside pyroluria

Your health care provider may request other tests when pyrrole disorder has been picked up. These may include some or all of the following:

  1. Caeruloplasmin – copper binding capacity (blood)
  2. Copper (via serum, plasma, red cell or hair analysis)
  3. Zinc (via serum, plasma, red cell or hair analysis)
  4. Zinc to Copper ratio -ideal is 10:1 – (blood or hair)
  5. Vit D (blood)
  6. Histamine levels (blood)
  7. Homocysteine (blood)
  8. B12 and folate levels  (blood)
  9. MMA (Methyl Malonic acid – more accurate indication of B12 – blood)
  10. MTHFR gene SNP defects (blood or oral swab)
  11. Other genetic testing (oral swab)
  12. Neurotransmitter testing (urine)
  13. Amino Acid testing (urine or blood)
  14. Thyroid and other hormone testing such as adrenal

Understanding Caeruloplasmin, copper and zinc

Caeruloplasmin is a protein made by your liver and its role is to carry copper via your blood plasma around your body to the tissues that need it. As well as being a major copper-carrying protein, Caeruloplasmin is also essential in effective iron metabolism. A deficiency of Caeruloplasmin is known as Aceruloplasminemia, and this issue crops up quite a bit with copper toxicity-related conditions.

A deficiency of Caeruloplasmin is strongly associated with copper toxicity and if left free and unbound, copper becomes a powerful free radical, resulting in oxidative stress, cell and tissue destruction, neurological degeneration, and a list of health-related issues. Some of these issues include:

  • Pyrrole disorder
  • Oestrogen dominance
  • Schizophrenia
  • Depression
  • Anxiety disorder
  • Chronic fatigue
  • Migraines
  • Liver toxicity
  • Thyroid conditions
  • Chronic candidiasis
  • Alzheimer’s Disease
  • Cardiovascular disease
  • Cancer
  • Alzheimer’s
  • Parkinson’s
  • OCD
  • ADD & ADHD
  • Rheumatoid arthritis

Perhaps one of the primary mechanisms through which copper toxicity can damage tissues is through oxidative stress and free radical formation. Free copper ions that are not bound to copper proteins such as Caeruloplasmin, are pro-oxidants, and are highly damaging.

While copper toxicity is a major cause for concern, it is something that can be effectively dealt with by powerful nutritional therapies and we need to also remember that Copper is a very important trace element that has many important roles in the body. These include:

  • Connective tissue formation
  • Nerve conduction
  • ATP synthesis
  • Iron metabolism
  • Brain health via neurotransmitter synthesis
  • Gene transcription
  • Synthesis of the antioxidant superoxide dismutase
  • Skin pigmentation
  • Nerve tissue: myelin sheath formation
  • Blood vessel formation

In a rare inherent disorder called Wilson disease, copper is not put into Caeruloplasmin and also keeps your liver from sending extra copper to be eliminated via your bowel movements so that copper then builds up in your liver until it overflows into the bloodstream which can then build up in your brain, corneas, kidneys, liver, bones, and small glands near the thyroid. If not treated, the liver and brain damage from copper poisoning can be fatal.

Whilst Wilson’s disease is a rare condition, there can be other situations where the copper is not fully bound to Caeruloplasmin and therefore toxically high levels of copper can be in the blood plasma with a concurrent copper deficiency at a cellular level. This can be balanced by addressing mineral and metal imbalances, adrenal fatigue, hormone imbalances and healing any gut issues.

Lower-than-normal Caeruloplasmin levels may indicate:

  • Wilson disease – excess storage of copper (genetic)
  • Menkes disease (kinky hair syndrome- genetic)
  • Overdose of Vitamin C
  • Copper deficiency at a cellular level, but may have high plasma levels (check the difference between plasma and hair results)
  • Aceruloplasminemia – lack of Caeruloplasmin

Greater-than-normal Caeruloplasmin levels may indicate or be noticed in:

  • copper toxicity with zinc deficiency, common with over methylation
  • pregnancy, oral contraceptive pill use and hormonal imbalances incl adrenal
  • lymphomas
  • acute and chronic inflammation such as Rheumatoid arthritis, Angina
  • Alzheimer’s disease
  • Schizophrenia & Obsessive-compulsive disorder

Disturbances of copper metabolism are very common, but a true copper deficiency is relatively uncommon, perhaps affecting 5-10% of the population, but could potentially become an issue with the over use of zinc supplementation when treating pyroluria. The treatment for high copper is both molybdenum and zinc. Caeruloplasmin levels a usually comparable to hair copper levels, but it is good to test both hair and blood to see the relationship to each other.

The roles of Zinc in the body

Zinc and copper are antagonists, meaning that increasing one can lower the other. While zinc toxicity is possible, far more common is zinc deficiency and copper toxicity. Zinc is an essential trace element that activates several hundred enzymatic reactions that are fundamental to a healthy life. Some of the activities that zinc are involved in are:

  • DNA & RNA synthesis
  • Gene expression
  • Nervous system function
  • Immune function & immune signalling such as cell apoptosis
  • Neuronal transmission
  • Brain function
  • Zinc possesses powerful anabolic activities in the cells
  • Formation of zinc proteins known as “zinc fingers”
  • Zinc is essential for blood clotting and platelet formation
  • Zinc is involved in Vitamin A synthesis
  • Folate is made available through zinc enzyme reactions
  • Along with copper, Zinc makes up the antioxidant enzyme system, ZnCu superoxide dismutase
  • Steroidal hormone synthesis
  • Growth & development of children
  • Testosterone and semen formation
  • The highest concentration of zinc is found in the male prostate gland

Some Causes of Copper Toxicity

  • Genetic Mutations that negatively alter copper-transport proteins such as Caeruloplasmin (CP gene). Genetic mutations that influence or cause the development of Huntington’s (HTT gene) and Wilson’s (ATP7B copper transport gene)
  • Environmental Copper Toxicity. Sources include: Copper pipes, dental fillings, copper-contaminated foods, contaminated municipal drinking water containing copper sulphate as an anti-fungal, copper IUD’s, copper fungicides, copper cookware and jewellery. (Note: copper pipes combined with water softening or heating will increase the leaching of copper and other toxic metals by making water acidic).
  • Nutrient Deficiencies: vegetarian and vegan diets (tend to be high in copper and low in zinc), zinc deficiency, pyrrole disorder
  • Increased Oxidative Stress: Deficiencies in the expression of cellular antioxidants such as metallothionein and glutathione, both of which bind to free copper ions

Nutritional Solutions for Copper Toxicity

High doses of any one nutrient, has the capability of altering other important nutrients in the body due to their relationship to each other. It is important to understand that if you have copper toxicity, taking too many copper antagonists can actually result in a copper deficiency. Therefore it is important to be consulting with an experienced practitioner to support you in choosing the right supplement regime and monitor your levels.

The following nutrients are primarily used to antagonize copper:

  • Zinc
  • Molybdenum
  • Manganese
  • Arachadonic acid (omega 6)
  • Sulfur (sulfur amino acid cysteine is essential for the formation of glutathione and metallothionein, both of which bind to free copper)
  • Vitamin B-6

The following nutrients have been shown to protect against copper-induced oxidative damage:

  • Vitamin E
  • Vitamin C
  • Glutathione
  • Alpha Lipoic Acid
  • Beta Carotene
  • Polyphenols

In summary, copper toxicity is a major cause of concern, and is likely a key player in many of today’s major health imbalances and diseases. Zinc, copper and Caeruloplasmin screening tests are an inexpensive yet powerful way to monitor your levels, and from these, individualised nutritional therapies can be offered.

NutriPath Lab offer a ‘Pfeiffer Profile’ test code – 3415 which includes; Plasma Zinc, serum Copper, Caeruloplasmin, whole blood Histamine, Homocysteine, Vitamin D3, Zn:Cu ratio all for only $185.00 plus lab initiation fee of $20 if you have never used the lab before, plus the pathology blood collection fee which varies depending on the collection centre. For a kit to be organised for you, please contact the True Vitality clinic via the contact page and I can organise to send you the kit needed (plus any other kits)

Hair analysis of heavy metals, minerals and ratios (HMMT) can be done via hair kit which is available on the True Vitality Shop. You will need the pass-code ‘vitality’ to gain access. Please note that you are NOT able to purchase supplements until you have register as a client after a consultation, so please don’t use the code to buy products or your order will be blocked. Thank you.

More info to come on the other tests….

The many faces/causes of Anxiety

The Many Faces of Anxiety

by Sue Kira N.D, PTC, DRM, PGD. Clin Nutri.

Anxiety is a multidimensional problem that faces far too many people today, but what causes anxiety? Below is a brief summary of some of the possible biochemical causes and support. Stress, psychological and emotional causes are not addressed here but are extremely important factors that must never be overlooked.

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Nutritional deficiencies

Nutritional deficiencies such as B vitamins, magnesium, calcium, potassium and vitamin C deficiency can all contribute to or exacerbate anxiety symptoms. These deficiencies can be caused by low intake, poor absorption or metabolic disorders and/or stress so the body then requires higher amounts of these nutrients. It is best to not self prescribe otherwise other imbalances can be created. Specific ratios of vitamins and minerals are required for balanced mental, emotional and physical health and well-being. 

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Allergies and intolerances

There are many common food and substance allergies that influence anxiety, such as food colors, preservatives, gluten or dairy intolerance or allergies. Many people who have been tested for allergies can have intolerances that may have been missed which can aggravate symptoms of anxiety. Food sensitivities that are not allergies can also be a problem, such as being sensitive to sugar caffeine or salicylates for example. For more information on allergies and intolerances please visit this article 

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Hormone imbalances

Hormone imbalances, especially thyroid levels, can give rise to anxiety symptoms. If a person has an under or overactive thyroid, then anxiety can be one of the many symptoms. Testing for thyroid levels in Australia can leave out many subclinical cases that could otherwise be helped by natural hormone support. PMS can be accompanied by increased anxiety, so balancing hormones in general can be a helpful support.

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Blood sugar imbalances

If a person’s blood sugar is not stable, is too high or especially if too low, this will surface any underlying anxiety that may not be otherwise noted. Blood sugar levels are dependent on the types of foods eaten (especially protein and carbohydrates) or how well they are digested as well as proper probiotic (friendly gut bacteria) levels. Another factor is dependent on if the pancreas is functioning properly or not.

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Metabolic disorders

Metabolic disorders such as pyrrole (aka pyroluria) are known to lead to an imbalance in specific vitamins and minerals. One of the more common symptoms of pyroluria is anxiety. Pyrrole disorder can be easily tested with a specific urine test and treatment is with specific nutrients. For more information on pyrrole disorder please visit this pyrrole article

Or Pyrrole Australia Face Book page https://www.facebook.com/PyrroleAustralia

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Heavy metal toxicity

Toxicity from heavy metals/minerals can also create imbalances that exacerbate anxiety. Sometimes a basic imbalance in the ratios of non toxic minerals can aggravate symptoms. Testing is best done by hair analysis. Metal and Mineral testing is available via the True Vitality clinic.

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Amino acid imbalances

Amino acids are the building blocks or individual parts of proteins. These are the needed co-factors for the production of neurotransmitters such as dopamine, serotonin, adrenaline (epinephrine) and nor-adrenaline (nor epinephrine). Amino acids and neurotransmitters can now be tested by urine to see if there are any crucial imbalances contributing to anxiety.

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Other factors

Other factors that could add to anxiety are: leaky gut syndrome, high copper levels, high histamine levels, other health problems/diseases, previous or current substance abuse leading to metabolic imbalances, reactions to medications, stress, caffeine, alcohol and much more.

For more articles on health and wellbeing please visit the articles page.

 

The above is a brief summary of conditions and imbalances that can add to anxiety. For more specific testing and assessments please visit your experienced local health care provider or Sue Kira at True Vitality. Appointments are available in clinic, via skype or phone sessions. For more information please email Sue via the contact page

 

Comments section below is for public viewing of your comments on the above article, so please don’t post questions or things you don’t wish to share. For more personal attention it is best to have a consultation to discuss your individual needs. Thank you, with love, Sue

Treating Insulin Resistance with food

Understanding Insulin Resistance and how to treat it with good food choices

Despite major changes in food production and technology, the eating habits of Western Society over the last few decades have resulted in record levels of chronic degenerative disease as well as a myriad of ‘minor disorders’ of digestive, respiratory and other systems.

Over 2000 years ago, Hippocrates advised his students to “let food be your medicine.” Every day experience tells us that our diet intimately affects our health and well being (remember the feeling of “I shouldn’t have eaten that!”)

Post war Western Society, indulged itself in an excess of refined carbohydrates and saturated fats, a trend that is now, even in orthodox medical circles, regarded as unhealthy.

The dietary advice of the last 20 years – initially from ‘alternative’ practitioners and later by mainstream medicos – has been to increase complex carbohydrates and fiber, and reduce fat and protein.  Current clinical experience, however, tells us this is still wrong.  The standard high complex carbohydrate, low fat, low protein diet has resulted in: raised serum insulin levels causing insulin resistance, reduction in basal metabolic rate, increased fat tissue growth and reduction in lean muscle mass, and accelerated biological ageing, common allergies to grains and dairy foods, immune system over activation and failure, and record amounts of heart disease, obesity and cancer.

The first point – insulin resistance

Insulin resistance is affecting the health of many people today.  The cell has only two ways to absorb the glucose it needs to make energy; insulin – mediated facilitated diffusion, and exercise – induced trans-membrane transport.  With the current trend towards an increasingly sedentary life style, insulin sensitivity becomes the controlling factor in cellular energy production.  If this is impaired, then every cell in the body is short of energy – and no matter what the cells function is, it needs energy to do it.

The obvious consequence of insulin resistance is fatigue, which I would have to say is the most common complaint I see in my clinic everyday.  But it goes a lot further than that; without cellular energy, muscle cells can’t contract or relax efficiently – this affects not only skeletal muscle, but also cardiac muscle, leading to cardiovascular disease; without cellular energy, endocrine cells can’t excrete hormones efficiently, resulting in hormonal imbalances; Immune cells don’t function properly resulting in infections, auto-immune diseases, cancer etc; bone cells cannot maintain bone density resulting in osteoporosis. Digestion is the most energy consuming function in the body – with insulin resistance, digestion is not effective.

So what causes insulin resistance?

Resistance to insulin can be caused by nutritional deficiencies like chromium, magnesium, selenium, taurine and/or essential fatty acids which can be assessed with Live Blood Screening, but is primarily a result of hyperinsulinaemia – which is too much insulin in the blood.

There are four main causes of hyperinsulinaemia?

1. lack of exercise, 2.stress, 3.toxin induced immune over activity and the 4.diet – wrong balance of carbohydrates to proteins and nutrient deficiencies.

The first two – exercise and stress require life style counseling and appropriate supportive supplementation and management.

With toxin-induced immune over activity – assessment of this would be done with consultation, Live Blood Screening and/or urine and saliva analysis, and correction requires integrated detoxification techniques utilizing detoxification diet, herbals and nutritionals to reduce the toxic burden on the body and cells.

Four key dietary programs may be involved in the reversal of insulin resistance:

1. The Insulin Zone System

2. The Ketogenic Fat Loss System

3. The A/B/O Blood Type Diet.

4. A fourth way which is even more profound but a total commitment to honesty with eating is vital, and that is to feel what foods best suit the body at any given time. This can only be done if first you have removed certain foods that inhibit you from truly feeling the right foods to eat. These foods are namely gluten, dairy and most starch foods, plus caffeine and alcohol as without removing these the body can be fooled by the interplay with foods and what they do to the body. More on this in another article.

The Insulin Zone System is an excellent program for educating anyone * towards the healthier eating patterns necessary to control blood glucose and insulin levels, thereby avoiding insulin resistance and the myriad of problems it brings.  Everyone will also benefit from the A/B/O diet.  You can use a combination of these two diets to get the best out of both.

Briefly the Zone Diet is about having 40 % of the diet ‘good’ carbohydrates, 30 % protein and 30 % ‘good’ fats.  The Insulin Zone System is great for everyone, * but especially those experiencing chronic tiredness, depression, poor circulation, hormonal imbalances including PMS, anxiety, hypertension, increased cholesterol, asthma and of course diabetes. * Obese people are unable to benefit from the Insulin Zone System because their body fat maintains circulating levels of fatty acids that perpetuate insulin resistance.

The adipose tissue must be reduced below critical percentages before the Insulin Zone System can take effect.  This loss of fat is achieved most effectively with the Ketogenic Fat Loss System.  Employing the A/B/O Blood Type Diet principles with the Ketogenic Fat Loss System will greatly improve results.

So how do you work out how much protein and carbs to eat to get a good ‘Insulin Zone’ balance?  The answer is in the palm of your hand.  The thickness and size of your palm is about the same volume as the amount of protein food that you need at each meal.  For snacks, use 1/3 of a palm of protein food.  Examples of protein may include – nuts, seeds, tofu, chicken, fish, eggs, lean beef/lamb, turkey etc.  For carbohydrates you can use the same method, except that you can have two palms of ‘good’ carbohydrate foods or one palm of ‘poor’ carbohydrates.

The ‘good’ carbs are all vegetables with the exclusion of the starchy veggies such as potato, sweet potato and corn have more nutrients and they won’t increase blood sugar/insulin levels as much as the ‘poor’ carbs such as bread, pastas, rice, potatoes, and sugar.

A more detailed listing of “good” and “poor’ carbohydrates as well as ‘good’ and ‘poor’ choices of fats and proteins are available from the clinic – Free with any session (please ask), as well as more information on the A/B/O Blood Type Diet, Ketogenic Fat Loss Diet and Detox Diet.

If you feel great and everything is in good working order and your diet works for you then stick with it.  These diets are choices available to assist people to make changes – remembering that no one diet suits all.

The A/B/O Blood Type Diet incorporates using ‘blood friendly’ foods specific to your blood type and avoiding those foods designated as having reactive ‘lectins’ – proteins that bind red blood cells – making them sticky often seen in Live Blood Screening. If you don’t know your blood type – this can be quickly determined with just a drop of blood from your finger in clinic.

Alcohol & Cigs- the Body's cry for stillness

Alcohol and cigarettes: the body’s cry for moments of stillness

When I am with clients who are suffering from fatigue, we discuss the things that may have been draining their energy.

Some share with me how they like to have a glass of wine or two at the end of each day to wind down. It can make the difference between them saying to their kids, “Ok it’s bath time darlings”, rather than angrily blurting out “get in the bath you little monsters or I’ll…!”

All they want is some peace and quiet at the end of the day. How often have we used a glass of wine, a cigarette or even a cup of tea or coffee to sit quietly and unwind? That moment when you have a sip of the drink, or drag on the cigarette and you are totally focused on the moment; think about it…the long drag in and then exhale with relief, or the sip, swallow and the ‘ahhhh’ as you breathe out with ‘relief’ and relaxation.

I realised that what people often miss when they give up these things is the time to simply relax and just ‘be’, because our bodies really crave moments of stillness.

I remembered how I did the same thing. These moments are our search for stillness, but the substances we choose to use actually take us away from true stillness. The caffeine in tea and coffee, the sugar in alcohol, and the nicotine in cigarettes, all make us racy, running faster inside than our natural rhythm.

At other times I would stop on my way home from work and just sit by the river to relax before going home to the family. It was a moment just for me; a moment of stillness to reflect and just ‘be’.

I chat with my clients about how easy it is to create moments of stillness that don’t have to be harmful to the body. By creating a space for ourselves of only a few minutes to sit, close our eyes, breathe very gently and feel our body, feet and eyes relaxing and our hands resting on our thighs, we can feel an absolute presence with ourselves. And then, by gently opening our eyes, we can hold that feeling of gentleness and presence and continue to be with ourselves.

When we share a few minutes of doing this together in the clinic, they are often amazed at how lovely they can feel in a very short time without substances, tapes or any cost and how they can do this at any time, even with their eyes open.

We may also discuss how being calm and present with children can bring them to gentleness and calmness. Some have noticed that when they are ‘actively present’ with their kids by maintaining eye contact and really connecting ‘with’ them, they are lovely and calm and less aggressive. They have also noticed that when they are stressed and cranky, the kids are harder to be with, which makes things worse for all.

If you would like to have this experience for yourself just ask when you come in for a consultation, and I will be very happy to share how easy this can be done.

Juices

In this article I thought I would talk about juices. We have all had such a long hot summer and many people have been feeling overly tired from the effects of the heat. I have had practically every person who has come in for a Live Blood Analysis complain of being excessively tired. Lots of people have been dehydrated, even though they seem to be drinking more water than usual, and most are mineral deficient, especially in Magnesium, a water soluble mineral.

A lot have been suffering the effects of toxicity, due also to dehydration. We’ve probably all had a toxic headache  from not drinking enough water at some time in our lives), as toxins are concentrated when we are dehydrated. It is very difficult to drink enough when it is so hot.

This is where the Ionised, alkaline water can help, as the smaller molecular structure helps the water to enter the cells of the body more easily, so it’s easier to stay hydrated (ring for more info if required).

Also fresh juices can help act as a “wetting” agent in the body. The best juices for this is apple juice, with it’s high pectin concentrations, also anything with chlorophyll in it, such as liquid chlorophyll, or anything green, such as wheat grass, barley grass, alfalfa, spinach, bock choy etc. and these also contain a rich source of magnesium. Fresh juice provides us with minerals, vitamins, essential fatty acids, carbohydrates, proteins and much more.

All these factors are vital to maintaining good health.  Although eating fruits and vegetables in their natural state provides us with adequate amounts of vitamins and minerals, we only obtain the maximum benefits from them when they are juiced, as much of their goodness is locked in the fibres which the body eventually expels.  However, when they are juiced, their goodness is released from the fibres and we are able to drink their highly concentrated nutrients which is then able to enter our bloodstream.

Very few people in today’s society eat enough raw fruit and vegetables.  The easiest way to start accommodating plenty of fresh fruits and vegetables into your diet is through juicing.  Juicing provides a quick and easy way to increase your consumption of these foods which would otherwise be hard to eat.  You will find when making your own fresh juices and including them in your daily diet, that you will have increased energy levels, a glowing complexion,  strengthened immune system, stronger bones and a reduced risk of disease.

Juices can also flush toxins from your body, are good for your weight, heart and circulation and general well being.  Juices contain no saturated fats or added sodium and can be helpful with lowering cholesterol.  Enzymes are also found in raw foods.  They are the life principle in atoms and molecules that make fresh “living foods” so easy to digest.   The quicker “living food” is eaten after juicing the more enzymes and nutrients are present.

There are many bottled juices available on the market today.  One of the problems with these bottled juices is that many of the valuable nutrients contained in fresh juices are lost during the bottling process.  Making your own juices and drinking them whilst still fresh ensures the control over the quality of the fruits and vegetables you are consuming as well as saving you money. Another way to utilise juices is in fasting programs.  

Juice Fasting is the most effective way to restore health and rejuvenate the body.  Although the old, classic form of fasting was a pure water fast, all the leading fasting authorities today agree that juice fasting is far superior to a water fast.  Fasting on fresh raw juices of fruit and vegetables, plus vegetable broths and herb teas, result in more effective cleansing and rejuvenation of the tissues than does the traditional water fast.

During the juice fast, the process of elimination of the dead and dying cells is speeded up, and the new-building of cells is accelerated and stimulated.  At the same time, the toxic waste products that interfere with the nourishment of cells are effectively eliminated and the normal metabolic rate and cell oxygenation are restored.

Vitamins, minerals, enzymes, trace elements and natural colorings of fresh, raw vegetable and fruit juices are extremely beneficial in normalising all the body processes, supplying needed elements for the body’s own healing activity and cell regeneration.  These juices require no digestion and are easily assimilated directly into the bloodstream. 

Mineral imbalance in the tissues is one of the main causes of diminished oxygenation, and consequent disease and premature aging.  Generous amounts of minerals in the juices help to restore the biochemical and mineral balance in the tissues and cells.  Also, raw juices contain an as yet unidentified factor which stimulates a micro-electric tension in the body and is responsible for the cells ability to absorb nutrients from the blood stream and effectively excrete metabolic wastes.

Here & Now Magazine March 2004

Coffee, the Great Liver Detoxifier? And the Gall Bladder Connection

Many people these days are in to doing a Liver and gall bladder flush using a heroic combination of olive oil and lemon juice, drunk in large quantities and followed by a chaser of Epsom salts.

There is no dispute as to the effectiveness of this therapy, as I have seen many a gall stone flushed this way myself, but another therapy for the good old Liver also bears mention, and this is in the use of coffee in an enema or colonic irrigation.

Max Gerson, famous for his treatments to cancer sufferers, uses coffee enemas as an integral part of his programs. Research has shown that enemas made from drip ground boiled coffee to prove themselves advantageous in restoring a dysfunctional liver. The caffeine drug in coffee administered rectally definitely detoxifies the liver.

During a 1985 conference on cancer treatment, specialist Harold Manner discussed the internal workings of a coffee enema, stating that while the coffee is being retained in the bowel for 12-15 mins., all of the body’s blood passes through the liver every three minutes.

The hemorrhoid blood vessels dilate from exposure to the caffeine, in turn the liver’s portal veins dilate too. Simultaneously, the bile ducts expand with blood, the bile flow increases, and the smooth muscles of these internal organs relax.

The blood serum and its’ many components get detoxified as the vital fluid passes through the individuals liver. The water being retained by the bowel stimulates the visceral nervous system promoting peristalsis (the rhythmical contractions of the colon).

So, much water delivered through the bowel dilutes the bile and causes an even greater increase in bile flow. There is a flushing of toxic bile which is further affected by the body’s enzymatic catalyst known as Glutathione-S-Transferase (GST).

The GST is increased in quantity in the small intestine by 700%, which is an excellent physiological effect, because this enzyme quenches free radicals. These quenched radicals leave the liver and gallbladder as bile salts flowing through the duodenum. The bile salts then get carried away by peristalsis in the gut, traveling from the small intestine, through the colon and out the rectum.

By now you may be wondering if drinking coffee can have the same effect, well unfortunately for coffee lovers it doesn’t. On the contrary, drinking coffee virtually ensures re-absorption of toxic bile. While other agents classed as stimulators of bile flow (choleretics) do increase bile production from the liver, they hardly enhance any detoxifying by that organ’s enzyme systems.

Instead, choleretics do nothing to ensure the passage of bile from the intestines. It’s a physiologic fact that bile is normally reabsorbed up to ten times by the body before working its’ way out of the intestines. The enzyme-intensifying ability of the coffee enema is unique among choleretics, because it does not allow re-absorption of toxic bile by the liver across the gut wall, so it is an effective means of detoxifying the blood stream through existing enzyme systems in both the liver and small intestines.

These enzyme systems are responsible for the conversion and neutralisation of the four most common tissue toxins, polyamines, ammonia, toxic-bound nitrogen, and electrophiles, all of which can cause cell and membrane damage.

Such protective gut and liver enzyme systems are massively increased in their beneficial effects by coffee enemas or colonics.

In summary research has shown that coffee administered rectally will accomplish the following physiological benefits: It dilutes portal blood and subsequently, the bile. Theophylline and theobromine, major nutriceutical constituents of coffee, dilate blood vessels and counter inflammation of the gut. The palmitates of coffee enhance glutathione-S-transferase which is responsible for removal of many toxic radicals from blood serum.

After many years of personally using coffee colonics in the clinic for not only people with cancer or other debilitating diseased states but also for general detoxification of the liver, and explaining how it works to many people along the way ,I hypothisised the thought that if the vein inside the rectum otherwise known as the hemorrhoid vein is dilating and causing subsequent dilation of the hepatic portal vein at the liver and gallbladder end of the body, then the reverse might also be true .

That is if the hemorrhoid vein is constricted such as in hemorrhoids then the hepatic portal vein may also be constricted meaning that the bile isn’t flowing from the liver and or gallbladder and may be due to obstruction due to gallstones or at least congestion of this area. This is only a hypothesis of mine but the more I talk to people about their condition the more this seems to be proven right.

Some people get hemorrhoids from pushing in childbirth or from constipation. The constipation often as a result of inadequate bile flow, as bile acts as a natural laxative, consequently people with loose stools often have too much bile flow happening due to an overactive gallbladder.

As for childbirth, I can relate to popping a hemmy from pushing the bub out, but this disappeared after a short healing process, so there shouldn’t be a hemmy years after child birth unless something is still happening to aggravate the situation.

Plus men don’t have babies but often have hemorrhoids. I have also noticed that not everyone is aware they have a hemorrhoid as these are often internal. To finish of, I would like to say that coffee administered rectally can be a helpful adjunct to any health therapy whether you have any problems with bowels, liver, gallbladder or not, as to have good liver health is to LIVE®

Here & Now Magazine April 2004

Fat Locked Toxins

As a clinic that specialises in detoxification I have employed over the last 11 years the use of various methods to detoxify the body.  The addition to the clinic of Live Blood Screening as a tool to identify what needs to be addressed has been extremely helpful as well as the use of Colonic Irrigation, herbs and the new Far Infra Red Sauna has seen many people regain and maintain good health.  But the body is very clever at holding onto certain resistant toxins.

These being mainly pesticides, herbicides, paint solvents and toxic metals.  These toxins are locked into the fatty components of various tissues such as fat itself and neuronal (nerve) tissue.  Water soluble techniques will not allow the release of these toxins and if they do, they are usually reabsorbed on the way out.

Over the years I have noticed a definate increase in the amount of people with chemical sensitivity.  Chemicals accumulated in the body produce chemical sensitivity.  Now I know you might be thinking, I have not been exposed to any chemicals and eat organically so it’s not my problem?  Well it propbably is.  If you have known chemical exposure then the problem could be even worse. 

Just a bit of personal history to bring home this point. Nearly 18 years ago when I was breast feeding my first child, it seemed that he didn’t want to feed very easily, so being the analytical person that I am, first thing I thought of was what was wrong with the milk, and because I had been working in a pathology lab, I thought I’d get my milk tested.  Well I was blown away with the test results as I had above acceptable levels of PCB’s, Chlordane, Heptachlor, Dieldrin and the list goes on and yes this is a person with no known chemical exposure.

In Sherry Rogers book “Detoxify or Die” she states research of the American Environmental Protection Agency study of 400 Americans and showed 100%, yes every single person studied had stores of carcinogens such as Dioxins, PCB’s, Dichlorobenzene, Styrene and Xylene just to name a few and research from Turusov of the World Health Organisation states “There are probably no clean pesticide free animal, fish or human left on the face of earth”. 

Since that time nearly 18 years ago I have been on a mission to clean myself of these toxic chemicals and to a certain degree, with the tools I have available I have been able to achieve this, but I find that I am still sensitive to some chemicals, such as if a client comes into the clinic wearing a strong smelling perfume I get a headache or sneeze.

So more recently, I used specialised herbs and healing techniques to clear these resistant toxins.  This is a process of deep tissue cleansing which is used after the initial removal of more water soluble toxins through Colon Hydrotherapy, herbs, Far Infra Red Saunas and liver regeneration.

What Are Heavy Metals?  There is actually no precise definition for the term “heavy metal” in chemistry.  The term is really slang for polluting metal ions that are persistant and potentially toxic in the environment.  A more meaningful term is therefore metal toxicity and the most commonly encountered toxic metals are aluminium, cadmium, lead, mercury and nickel.  Toxic metals tend to accumulate in fatty tissues, if there are indications of  metal toxicity you may opt to add clearance of toxic metals to the deep tissue cleanse process. 

Aluminium; associated with: Alzheimer’s Disease, Parkinson’s Disease, Dementia, Psychosis, Osteomalacia, muscle pain, colic, gastroenteritis, liver dysfunction, microcytic hypochromic anaemia. 

Cadmium; ass. with: hair loss, (alopecia), dry scaly skin, yellow teeth, osteoporosis, kidney and liver damage, increased blood pressure, fatigue, emphysema. 

Lead; ass. with: behavioural abnormalities, cognitive impairment, uncoordination, depression, dizziness, fatigue, headaches, restlessness, anaemia, anorexia, constipation, muscle and bone pain, peripheral neuropathy. 

Mercury ass. with: depression, emotional instability, loss of vision or hearing, tremors, weak, tired, psychotic and thirst. 

Lead ass with:  skin allergies, fever, insomnia, headaches, nausea, vomitting, diarrhoea, short or rapid breathing, apathy. 

The above deep tissue cleanse and toxic metal clearance program marks the start of our new improved Ultimate Tissue Cleanse.

Here & Now magazine May 2004

The above program is no longer available, but you may contact the clinic for an alternative. 3/11/09